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web del Instituto de Biología Molecular y Celular
Dr. Carmen Reyes Mateo Martínez

Unit: Molecular and Cellular Design
Subunit: Molecular Recognizement and Protein Engineering
Group: Fluorescent Sensor Group
Category: Investigator
Phone: + 34 966 65 84 77
Degree: Chemistry
Ph.D program: PhD degree in Chemistry, Universidad Autonoma de Madrid (Director: Dr. A. Ulises Acuña), 1989.
Postdoctoral positions: 1.- Laboratoire pour l’utilisation du rayonnement electromagnetique (L.U.R.E.-CNRS- Université Paris-Sud, Orsay, France. Time-resolved fluorescence experiments using synchrotron radiation: application to the characterization of biological systems. (1990-1993).
2.- Instituto de Química Física “Rocasolano”, CSIC, Madrid, Spain. Spectroscopic characterization of new fluorescent probes for biological applications (1994-1996).
Previous positions:
Fellowship from Ministerio de Educación y Ciencia, Instituto de Química Física, CSIC, Madrid. Spain. 1986-1989.
Current Position: Professor of Chemistry, Universidad Miguel Hernández (since 1997).
Research Fields:
1.- Application of fluorescence spectroscopy to the biophysical characterization of biological systems in non-conventional environments.
2.- Fluorescent biosensor development.
3.- Characterization of macromolecular interactions.
Representative Publications:

  • Formation of complexes between the conjugated polyelectrolyte poly{[9,9-bis(6'-n,n,ntrimethylammonium) hexyl]fluorene-phenylene} bromide (HTMA-PFP) and human serum albumin. M.J. Martínez-Tome, R. Esquembre, R. Mallavia, C.R., Mateo. 2010. Biomacromolecules 11(6), 1494-1501.
  • Biophysical and functional characterization of an ion channel Peptide confined in a sol-gel matrix. R. Esquembre, J.A. Poveda, C.R. Mateo. 2009. J. Phys. Chem. 113(21), 7534-7540.
  • Immobilization of a trienzymatic system in a sol-gel matrix: A new fluorescent biosensor for xanthine. A. Salinas-Castillo, I., Pastor, R. Mallavia, C.R., Mateo. 2008. Biosensors and Bioelectronics 24(4), 1053-1056.
  • Effect of sol-gel confinement on the structural dynamics of the enzyme bovine Cu,Zn superoxide dismutase. I. Pastor, M. Prieto, M., C.R. Mateo, 2008. J. Phys. Chem. B 112(47), 15021-15028.
  • Fluorescence study of the fluidity and cooperativity of the phase transitions of zwitterionic and anionic liposomes confined in sol-gel glasses. R. Esquembre, M.L. Ferrer, M.C. Gutierrez, R. Mallavia, C. R. Mateo. Journal of Phys. Chem. B 111(14), 3665-3673.

Patents & Available Technologies:
Production of new polymer liquid crystals capable of having an interaction with liposomes. Pub. No.: WO/1998/031347. International Application No.: PCT/ES1998/000005. Inventors: M.M. Pérez-Méndez and C.R. Mateo. Proprietor: CSIC. Date of publication: 23.07.1998