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Próxima lectura de Tesis Doctoral en el IDiBE: Evaluación de los genes MGMT, SOCS1 y SOCS3 como marcadores moleculares de quimio y radiorresistencia en modelos celulares de glioblastoma humano (Jueves 11 de Julio de 2019 a las 11:30).

Publication highlights

Arribas-Blázquez, M.; Olivos-Oré, L. A.; Barahona, M. V.; de la Muela, M. S.; Solar, V.; Jiménez, E.; Gualix, J.; McIntosh, J. M.; Ferrer-Montiel, A.; Miras-Portugal, M. T.; Artalejo, A. R. Overexpression of P2X3 and P2X7 receptors and TRPV1 channels in adrenomedullary chromaffin cells in a rat model of neuropathic pain. International Journal of Molecular Sciences 2019, 20 (1), DOI: 10.3390/ijms20010155.

Bello-Perez, M.; Falco, A.; Novoa, B.; Perez, L.; Coll, J. Hydroxycholesterol binds and enhances the anti-viral activities of zebrafish monomeric c-reactive protein isoforms. PLoS ONE 2019, 14 (1), DOI: 10.1371/journal.pone.0201509.

Bello-Perez, M.; Medina-Gali, R.; Coll, J.; Perez, L. Viral interference between infectious pancreatic necrosis virus and spring viremia of carp virus in zebrafish. Aquaculture 2019, 500, 370-377 DOI: 10.1016/j.aquaculture.2018.10.039.

Chico, V.; Salvador-Mira, M. E.; Nombela, I.; Puente-Marin, S.; Ciordia, S.; Mena, M. C.; Perez, L.; Coll, J.; Guzman, F.; Encinar, J. A.; Mercado, L.; Ortega-Villaizan, M. D. M. IFIT5 Participates in the Antiviral Mechanisms of Rainbow Trout Red Blood Cells. Frontiers in immunology 2019, 10, 613 DOI: 10.3389/fimmu.2019.00613.

Cuy�s, E.; Verdura, S.; Lozano-Sánchez, J.; Viciano, I.; Llorach-Parés, L.; Nonell-Canals, A.; Bosch-Barrera, J.; Brunet, J.; Segura-Carretero, A.; Sanchez-Martinez, M.; Encinar, J. A.; Menendez, J. A. The extra virgin olive oil phenolic oleacein is a dual substrate-inhibitor of catechol-O-methyltransferase. Food and Chemical Toxicology 2019, 128, 35-45 DOI: 10.1016/j.fct.2019.03.049.

de la Luz Cádiz-Gurrea, M.; Micol, V.; Joven, J.; Segura-Carretero, A.; Fernández-Arroyo, S. Different behavior of polyphenols in energy metabolism of lipopolysaccharide-stimulated cells. Food Research International 2019, 118, 96-100 DOI: 10.1016/j.foodres.2018.02.027.

Dos Santos, R. S.; Marroqui, L.; Velayos, T.; Olazagoitia-Garmendia, A.; Jauregi-Miguel, A.; Castellanos-Rubio, A.; Eizirik, D. L.; Casta�o, L.; Santin, I. DEXI, a candidate gene for type 1 diabetes, modulates rat and human pancreatic beta cell inflammation via regulation of the type I IFN/STAT signalling pathway. Diabetologia 2019, 62 (3), 459-472 DOI: 10.1007/s00125-018-4782-0.

Esteban, J.; Serrano-Maciá, M.; Sánchez-Pérez, I.; Alonso-Magdalena, P.; Pellín, M. D. L. C.; García-Arévalo, M.; Nadal, á.; Barril, J. In utero exposure to bisphenol-A disrupts key elements of retinoid system in male mice offspring. Food and Chemical Toxicology 2019, 126, 142-151 DOI: 10.1016/j.fct.2019.02.023.

Giménez, T.; Mula, D.; Gea-Botella, S.; Martínez-Madrid, M. C.; Martí, N.; Valero, M.; Saura, D. Lipase catalyzed deacidification of tocopherol-rich distillates obtained from natural Vitamin E sources. Process Biochemistry 2019, 77, 70-76 DOI: 10.1016/j.procbio.2018.11.008.

Giudici, A. M.; Renart, M. L.; Díaz-García, C.; Morales, A.; Poveda, J. A.; González-Ros, J. M. Accessibility of cations to the selectivity filter of KcsA in the inactivated state: An equilibrium binding study. International Journal of Molecular Sciences 2019, 20 (3), DOI: 10.3390/ijms20030689.

Herranz-López, M.; Olivares-Vicente, M.; Boix-Castejón, M.; Caturla, N.; Roche, E.; Micol, V. Differential effects of a combination of Hibiscus sabdariffa and Lippia citriodora polyphenols in overweight/obese subjects: A randomized controlled trial. Scientific Reports 2019, 9 (1), DOI: 10.1038/s41598-019-39159-5.

Jung, M. H.; Chico, V.; Ciordia, S.; Mena, M. C.; Jung, S. J.; Ortega-Villaizan, M. D. M. The Megalocytivirus RBIV Induces Apoptosis and MHC Class I Presentation in Rock Bream (Oplegnathus fasciatus) Red Blood Cells. Frontiers in immunology 2019, 10, 160 DOI: 10.3389/fimmu.2019.00160.

Martínez-Ortega, L.; Mira, A.; Fernandez-Carvajal, A.; Reyes Mateo, C.; Mallavia, R.; Falco, A. Development of a new delivery system based on drug-loadable electrospun nanofibers for psoriasis treatment. Pharmaceutics 2019, 11 (1), DOI: 10.3390/pharmaceutics11010014.

Medina-Carmona, E.; Rizzuti, B.; Martín-Escolano, R.; Pacheco-García, J. L.; Mesa-Torres, N.; Neira, J. L.; Guzzi, R.; Pey, A. L. Phosphorylation compromises FAD binding and intracellular stability of wild-type and cancer-associated NQO1: Insights into flavo-proteome stability. International Journal of Biological Macromolecules 2019, 125, 1275-1288 DOI: 10.1016/j.ijbiomac.2018.09.108.

Medina-Gali, R.; Belló-Pérez, M.; Ciordia, S.; Mena, M. C.; Coll, J.; Novoa, B.; Ortega-Villaizán, M. D. M.; Perez, L. Plasma proteomic analysis of zebrafish following spring viremia of carp virus infection. Fish and Shellfish Immunology 2019, 86, 892-899 DOI: 10.1016/j.fsi.2018.12.035.

Neira, J. L.; Díaz-García, C.; Prieto, M.; Coutinho, A. The C-terminal SAM domain of p73 binds to the N terminus of MDM2. Biochimica et Biophysica Acta - General Subjects 2019, 1863 (4), 760-770 DOI: 10.1016/j.bbagen.2019.01.019.

Nikolaeva Koleva, M.; Fernandez-Ballester, G., In silico approaches for TRP channel modulation. In Methods in Molecular Biology, 2019; Vol. 1987, pp 187-206.

Pantoja-Uceda, D.; Neira, J. L.; Contreras, L. M.; Manton, C. A.; Welch, D. R.; Rizzuti, B. The isolated C-terminal nuclear localization sequence of the breast cancer metastasis suppressor 1 is disordered. Archives of Biochemistry and Biophysics 2019, 664, 95-101 DOI: 10.1016/j.abb.2019.01.035.

Pérez-Sánchez, A.; Barrajón-Catalán, E.; Ruiz-Torres, V.; Agulló-Chazarra, L.; Herranz-López, M.; Valdés, A.; Cifuentes, A.; Micol, V. Rosemary (Rosmarinus officinalis) extract causes ROS-induced necrotic cell death and inhibits tumor growth in vivo. Scientific Reports 2019, 9 (1), DOI: 10.1038/s41598-018-37173-7.

Pérez-Sánchez, A.; Cuy�s, E.; Ruiz-Torres, V.; Agulló-Chazarra, L.; Verdura, S.; González-álvarez, I.; Bermejo, M.; Joven, J.; Micol, V.; Bosch-Barrera, J.; Menendez, J. A. Intestinal permeability study of clinically relevant formulations of silibinin in caco-2 cell monolayers. International Journal of Molecular Sciences 2019, 20 (7), DOI: 10.3390/ijms20071606.

Renart, M. L.; Giudici, A. M.; Poveda, J. A.; Fedorov, A.; Berberan-Santos, M. N.; Prieto, M.; Díaz-García, C.; González-Ros, J. M.; Coutinho, A. Conformational plasticity in the KcsA potassium channel pore helix revealed by homo-FRET studies. Scientific Reports 2019, 9 (1), DOI: 10.1038/s41598-019-42405-5.

Rodríguez-Laiz, G. P.; Zapater, P.; Melgar, P.; Alcázar, C.; Franco, M.; Giménez, P.; Pascual, S.; Bellot, P.; Palazón, J. M.; Rodríguez, M.; Carnicer, F.; Más-Serrano, P.; González-Navajas, J. M.; Gómez, L.; Such, J.; Lluís, F.; Francés, R.; de Santiago, C.; Navarro, J.; Martínez, F.; Galiana, M.; Salas, E.; Palomar, I.; Irurzun, J.; Bernabé, J. M.; Perdiguero, M.; Díaz, M.; Lozano, T.; Merino, E.; Almanza, S.; Mataix, J. M.; Orts, P.; Jaime, F. Bacterial DNA translocation contributes to systemic inflammation and to minor changes in the clinical outcome of liver transplantation. Scientific Reports 2019, 9 (1), DOI: 10.1038/s41598-018-36904-0.

Sánchez-Marzo, N.; Pérez-Sánchez, A.; Ruiz-Torres, V.; Martínez-Tébar, A.; Castillo, J.; Herranz-López, M.; Barrajón-Catalán, E. Antioxidant and photoprotective activity of apigenin and its potassium salt derivative in human keratinocytes and absorption in Caco-2 cell monolayers. International Journal of Molecular Sciences 2019, 20 (9), DOI: 10.3390/ijms20092148.

Soriano, S.; Castellano-Mu�oz, M.; Rafacho, A.; Alonso-Magdalena, P.; Marroquí, L.; Ruiz-Pino, A.; Bru-Tarí, E.; Merino, B.; Irles, E.; Bello-Pérez, M.; Iborra, P.; Villar-Pazos, S.; Vettorazzi, J. F.; Montanya, E.; Luque, R. M.; Nadal, á.; Quesada, I. Cortistatin regulates glucose-induced electrical activity and insulin secretion in mouse pancreatic beta-cells. Molecular and Cellular Endocrinology 2019, 479, 123-132 DOI: 10.1016/j.mce.2018.09.009.

Ventero, M. P.; Fuentes-Baile, M.; Quereda, C.; Perez-Valeciano, E.; Alenda, C.; Garcia-Morales, P.; Esposito, D.; Dorado, P.; Barbera, V. M.; Saceda, M. Radiotherapy resistance acquisition in glioblastoma. Role of SOCS1 and SOCS3. PLoS ONE 2019, 14 (2), DOI: 10.1371/journal.pone.0212581.

Yadahalli, S.; Neira, J. L.; Johnson, C. M.; Tan, Y. S.; Rowling, P. J. E.; Chattopadhyay, A.; Verma, C. S.; Itzhaki, L. S. Kinetic and thermodynamic effects of phosphorylation on p53 binding to MDM2. Scientific Reports 2019, 9 (1), DOI: 10.1038/s41598-018-36589-5.

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