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web del Instituto de Biología Molecular y Celular
Dr. Jose Antonio Poveda Larrosa

Unit: Molecular and Cellular Design
Subunit: Structure-Function Relationships in Membrane Proteins
Group: Structure-function relationship of potassium channels
Category: Investigator
Phone: + 34 966 65 84 66
Email: ja.poveda@umh.es
Degree: Chemistry
Ph.D program:
PhD degree with Honors at the Neuroscience program, Universidad Miguel Hernández de Elche (Director: Prof. José Manuel González Ros and C. Reyes Martínez Mateo, 2002)
Previous positions:
1.- Predoctoral Fellowship from Ministerio de Educación y Cultura of Spain, University of Alicante. Department of Neurochemistry. 1997-2000.
2.- Assistant professor, University Miguel Hernandez, 2001-2005
Current Position: Professor of Physical Chemistry, Universidad Miguel Hernandez.
Research Fields:

  • Structure-function relationship in membrane proteins.
  • Lipid-protein interactions.
  • Modulation of ion channel structure and function.

Representative Publications:
  • Poveda JA, Giudici AM, Renart ML, Molina ML, Montoya E, Fernández-Carvajal A, Fernández-Ballester G, Encinar JA, González-Ros JM. Lipid modulation of ion channels through specific binding sites. Biochim Biophys Acta. 2014, 1838: 1560-7.
  • Giudici AM, Molina ML, Ayala JL, Montoya E, Renart ML, Fernández AM, Encinar JA, Ferrer-Montiel AV, Poveda JA, González-Ros JM. Detergent-labile, supramolecular assemblies of KcsA: relative abundance and interactions involved. Biochim Biophys Acta. 2013, 1828: 193-200.
  • Renart ML, Montoya E, Fernández AM, Molina ML, Poveda JA, Encinar JA, Ayala JL, Ferrer-Montiel AV, Gómez J, Morales A, González Ros JM. Contribution of ion binding affinity to ion selectivity and permeation in KcsA, a model potassium channel. Biochemistry. 2012, 51: 3891-900.
  • Renart ML, Triano I, Poveda JA, Encinar JA, Fernández AM, Ferrer-Montiel AV, Gómez J, González Ros JM. Ion binding to KcsA: implications in ion selectivity and channel gating. Biochemistry. 2010, 49: 9480-7.
  • Triano I, Barrera FN, Renart ML, Molina ML, Fernández-Ballester G, Poveda JA, Fernández AM, Encinar JA, Ferrer-Montiel AV, Otzen D, González-Ros JM. Occupancy of nonannular lipid binding sites on KcsA greatly increases the stability of the tetrameric protein. Biochemistry. 2010, 49: 5397-404.